WS Overview

Wolfram syndrome overview

Wolfram syndrome, also known as DIDMOAD which represents (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), is an inherited rare genetic disorder that affects multiple systems in the body. The disorder is named after Dr. Warren T. Wolfram, who first described the condition in 1938. It is estimated to affect one in 500,000 people worldwide.

Causes of Wolfram Syndrome:​

In most cases, Wolfram syndrome is caused by a mutation in the WFS1 gene. This gene plays a role in the proper functioning of cells throughout the body.

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